From Florence:
Leaving Florence-Certosa go on for Florence to Siena.
From Siena go to Grosseto on S.S. 223. To Grosseto turn down to the S.S. 1 Aurelia to Rome to Albinia. When you get to Albinia take the S.S. 74 to Marsiliana-Manciano-Orvieto, after Marsiliana, go straight to Manciano-Orvieto untill the 14.900 km and turn on the left on S.P. Guinzoni n° 150. Go on for 1.500 km then turn again to the left and go on for 2 km you’ll arrived.

From Rome:
Leaving Civitavecchia, go on S.S. 1 Aurelia direction Grosseto, pass the cross for Orbetello-Monte Argentario, go on S.S. 1 Aurelia for about 15 km, untill km 146, then turn right to Manciano Saturnia. To go on untill the cross S.S. 74 and turn right to Marsiliana-Manciano-Orvieto. After Marsiliana, go in direction Manciano-Orvieto untill the km 14.900 and turn left on S.P. Guinzoni n° 150 then go along for km 1.500 then turn again on the left, go on for 2 km and you'll arrive.

From Orvieto:
From the motorway A1 leave Orvieto and take direction to C.S. Giorgio, S. Lorenzo Nuovo, then go for Pitigliano-Manciano S.S.74, follow the S.S.74 after Manciano, untill the km 14.900 then turn right on S.P. Guinzoni n° 150.
Go on for km 1.500, then turn left, go on for km 2.00 and you'll arrive.